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Pharmacy News

Study finds possible risk of birth defects with first trimester use of methadone versus buprenorphine

Both buprenorphine and methadone treat OUD, but there is limited understanding of how in-utero exposure affects infants. Researchers of a new study published in JAMA Internal Medicine used Medicaid data to gauge the risk of congenital malformations in neonates whose mothers received buprenorphine or methadone while carrying them.

FDA adds boxed warning to denosumab specific for patients with advanced CKD

FDA added a boxed warning to the osteoporosis drug denosumab (Prolia). The agency’s review of the drug indicated risks that warrant new prescribing information. For patients with chronic kidney disease (CKD)—especially those on dialysis or those with a concomitant diagnosis of mineral and bone disorder—FDA said they could develop severe hypocalcemia, or very low levels of calcium in the blood.

CDC releases detailed adult immunization schedule for 2024, with revisions

CDC’s adult immunization schedule for 2024, which was published in the Annals of Internal Medicine on January 12, 2024, includes updates for several vaccines, including those for respiratory syncytial virus (RSV), meningitis, mpox, and COVID-19. The immunization schedule is based on the recommendations of CDC’s ACIP.

Early tecovirimat treatment for mpox disease may benefit people with HIV

Early intervention with tecovirimat may stop an mpox infection from advancing to the stages of severe disease in people living with HIV (PWH), new research suggests.

Research looks at Paxlovid for long COVID risk

Paxlovid did not reduce the risk of developing long COVID in vaccinated, nonhospitalized adults, according to new data published in the Journal of Medical Virology.

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