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›› Calcium supplementation without vitamin D increases MI risk - According to a recent meta-analysis, calcium supplementation without coadministered vitamin D is associated with about a 30% increase in the risk of myocardial infarction.

›› Increased risk of death with Tygacil, FDA warns - FDA issues reminder that Pfizer antibiotic Tygacil has increased mortality risk compared to other antibiotics with similar indications.

›› Extended-duration enoxaparin thromboprophylaxis beneficial for some acutely ill medical patients - In a recent trial, extending enoxaparin prophylaxis for an additional 28 days after an initial 10-day course of therapy reduced the incidence of VTE. However, this beneficial effect was only seen in subgroups of patients with level 1 immobility, those older than 75 years, and women. Extended-duration enoxaparin was also associated with an increased risk of major bleeding events.

›› Delipidated HDL for acute coronary syndrome - In a first-in-man study, serial autologous delipidated HDL plasma infusions were clinically feasible and tolerated and safely increased HDL levels in patients suffering from acute coronary syndrome.

›› Meta-analysis: Statins do not decrease all-cause mortality - In a recent meta-analysis, statin therapy did not reduce all-cause mortality in high-risk patients who had no history of cardiovascular disease.

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›› 2010–11 influenza season: Key points -

›› New CDC data indicate 23,607 influeza-related deaths per year in U.S. - Data spanning 3 decades show fewer deaths than previous estimates.

›› FluZone High-Dose vaccine: Who should get it? - Vaccine is approved for use in patients 65 years or older, but ACIP is waiting for clinical trial evidence before making specific recommendations.

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›› APhA to DEA: Improve access to controlled substances in nursing homes

›› FDA's CDER advised by Drug Safety Oversight Board

›› All HCR News

Nominate a colleague for recognition from APhA! Nominate individuals and organizations that are making a difference in your area of practice or research for recognition at the 2011 APhA Annual Meeting & Exposition in Seattle, WA, March 25-28, 2011. Review the 2010 APhA Awards Guidebook for more details.

›› APhA Seeks Candidates for the 2011 APhA-APPM and APhA-APRS Elections

›› Board of Pharmacy Specialties Releases 2009 Annual Report

Shop APhA for the September book of the month, The APhA Complete Review for the FPGEE®, and receive 30% off the list price!
Be sure to mention offer code BOM2010.

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