After recent FDA-approved changes to the clozapine REMS program and the isotretinoin REMS program known as iPLEDGE, users of both programs are experiencing issues.

Maria G. Tanzi, PharmD

The use of direct oral anticoagulants for stroke prevention in patients with AFib can cause a risk of bleeding and therefore limits their use. A recent study from the OCEANIC–AF Steering Committee investigated the efficacy of asundexian, an activated factor XI inhibitor that may prevent strokes with less bleeding.

APhA Staff

SGLT-2 inhibitors have demonstrated significant efficacy in the management of heart failure. The American College of Cardiology, American Heart Association, and Heart Failure Society of America recommend SGLT-2 inhibitors for patients with heart failure with reduced ejection fraction (HFrEF) due to their substantial benefits in reducing cardiovascular death and heart failure hospitalizations.

Corey Diamond, PharmD

A recent study in The Journal of Clinical Hypertension examined the use of SGLT-2 inhibitors in reducing BP in patients with hypertension, including those who have been experiencing apparent treatment-resistant hypertension and proteinuria.

Elizabeth Briand

The COVID-19 pandemic shined a light on pharmacists’ relevant skills and expertise in the face of an infectious disease outbreak. Now that the smoke has cleared, pharmacists have largely returned to their prepandemic duties. But a working knowledge of infectious diseases and their treatment strategies continues to be essential across all pharmacy practice settings.

Sonya Collins