CDC recently approved new pneumococcal vaccine (PCV) recommendations. Now, CDC recommends the use of either 20-valent pneumococcal conjugate vaccine (PCV20) alone or 15-valent pneumococcal conjugate vaccine (PCV15) in series with 23-valent pneumococcal polysaccharide vaccine (PPSV23) for all adults aged 65 years or older and for adults aged 19 to 64 years with certain underlying medical conditions or other risk factors who have not previously received a PCV vaccine or whose previous vaccination history is unknown.

PCSK9 inhibitors appear to lower nonfatal myocardial infarction in adults with high or very high cardiovascular risk but not in those with low or moderate risk, according to a new study published in The BMJ.

CMS has issued a final rule that put an end to PBM’s retroactive application of direct and indirect remuneration (DIR) fees, requiring that they be reflected in the negotiated price the patient pays at the pharmacy counter. The rule included all price concessions beginning on January 1, 2024.

Antidepressants, including serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors, are widely used in the United States despite a number of unknowns related to their clinical performance. One of the biggest unknowns stems from the dearth of evidence on the efficacy of the drugs over the long term, as most studies have followed up with participants for only 8 to 12 weeks. Researchers also do not know much about how antidepressants affect mental and physical quality of life over time.

The US Preventive Task Force (USPSTF) has updated its 2016 recommendation on the use of aspirin to protect against cardiovascular disease (CVD) and colorectal cancer (CRC).