The Endocrine Society has released a statement telling clinicians to avoid using custom-compounded hormones to treat issues such as menopausal symptoms and thyroid disorders. During a press briefing, the lead author of the statement, Nanette Santoro, MD, of the University of Colorado School of Medicine in Aurora, said these hormones should only be used when patients are allergic or do not tolerate FDA-approved therapies. The statement is published in the Journal of Clinical Endocrinology and Metabolism. This opinion has been shared by other medical societies, but many physicians still prescribe custom-compounded, "bioidentical" hormones. These products can be dangerous because added excipients can affect absorption, and those or other added ingredients could be contaminated or adulterated. To make the point clearer, Santoro's team noted there are many FDA-approved formulations that are recommended for postmenopausal therapy, making nonapproved custom products unnecessary. The report noted that "there is no rationale" for the routine use of the unapproved products.