Hormone therapy for postmenopausal women

Hormone therapy (HT) is recommended for relief from hot flashes or night sweats in women younger than age 60 years or those who entered menopause within 10 years of seeking treatment.

Hormone therapy (HT) is recommended for relief from hot flashes or night sweats in women younger than age 60 years or those who entered menopause within 10 years of seeking treatment. HT also can reduce bone loss and the risk of fractures; offer a potential cardioprotective benefit; and alleviate the genitourinary symptoms of menopause, including dysfunction of the bladder and irritation of the vagina and vulva. However, as JoAnn V. Pinkerton, MD, of the University of Virginia Health System notes, the treatment is not without its risks, including concerns about cognitive decline and breast cancer. More research is warranted, she writes, to determine the long-term benefits and risks of menopausal HT, to gauge the effects of prolonged use in women initiating therapy close to menopause, to inform the timing of and approach to HT discontinuation, and to answer additional unknowns. As scientists work to address these questions, Pinkerton says that technology can help identify women likely to benefit from HT. The MenoPro mobile app, backed by the North American Menopause Society, provides a free algorithm to flag the strongest candidates.