Effectiveness of combined behavioral and drug therapy for OAB symptoms in men

New research provides important information for men experiencing symptoms of overactive bladder. The study examined the effects of combined behavioral and drug therapy for more than 200 men aged 40 years or older with urinary urgency and nine or more voids per 24 hours.

New research provides important information for men experiencing symptoms of overactive bladder. The study examined the effects of combined behavioral and drug therapy for more than 200 men aged 40 years or older with urinary urgency and nine or more voids per 24 hours. For the two-stage, multisite randomized clinical trial, participants were randomized to up to 6 weeks of behavioral therapy alone (including pelvic floor muscle training with urge suppression strategies and delayed voiding), drug therapy alone (including an antimuscarinic plus an alpha-blocker), or combined therapy followed by step-up to 6 weeks of combined therapy for all groups. Data for participants were collected from July 2010 and July 2015. According to the results, reductions in voiding frequency were much higher among men who received combined therapy compared with participants receiving drug therapy alone, but not compared with those receiving only behavioral therapy. After all groups had received combined therapy, improvements in mean voids per 24 hours were better for those who first received combined therapy, although there were no statistically significant group differences.